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Final Misson of Mass Effect 3 takes place on Earth. Otherwise once you leave at the start of the game, you can't go back until the end.

  • The places you see are Vancouver (beginning) and London (end).  JohnMD (talk)

You have to go back to Earth if you want to beat the game; it's where the final story mission takes place, and the only possible destination for the Normandy after Priority: Cerberus Headquarters. Terminator-HIX

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