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As far as I recall, the only romantic relationship that can progress on its own (without Shepard) is that of Tali and Garrus. No other pairs. Mitranim

  • They do hook up at the party in the Citadel DLC if Shepard encourages them, but it doesn't influence the game outside of that in any way, so I'm inclined to believe it's a one-time thing, like how Vega treats hooking up with a female Shepard at that party. Terminator-HIX

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